All products by Croma were created using revolutionary, patent-protected S.M.A.R.T. technology (Supreme Monophasic and Reticulated Technology). The S.M.A.R.T. process uses the well-established BDDE (butanedioldiglycidether) as reticulating agent to create a very dense HA network and perfectly clear gel consisting of very long, strong and stable chains of hyaluronic acid.