Natural vs. Synthetic-Based Fillers: What's the Difference?

Natural vs. Synthetic-Based Fillers: What’s the Difference?

Feb 12, 2024

Do you find it challenging to decide between natural and synthetic fillers for your patients’ facial rejuvenation? This dilemma is all too common for clinics and healthcare providers alike. As the demand for injectable dermal fillers continues to rise, the importance of selecting the most suitable solution for each patient becomes increasingly critical. In this post, we delve into the crucial question: What is the difference between natural and synthetic filler? Keep reading to learn more about diverse facial fillers and their effectiveness in treating fine lines and wrinkles.

Note: You can choose dermal fillers from an excessive range of cosmetic solutions on our website. Stay ahead of your colleagues and elevate your practice. Buy dermal fillers here!

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Natural Based Fillers

Natural fillers are injectable dermal fillers that combine natural components in the formulations. The ingredients of these injectable treatments are derived from substances found in the body or nature. They offer a harmonious approach to combating signs of the aging process and providing a natural look.

Composition and Functionality

Natural dermal fillers are mainly enriched with hyaluronic acid (HA). It is a naturally occurring sugar found in the human body: connective tissues, joint fluids, and skin tissue. As we age, the body’s natural collagen production decreases, leading to dryness, thinning skin, and the formation of fine lines and wrinkles. HA possesses an extraordinary ability to retain water. This unique quality allows it to maintain hydration and contribute to the skin’s plumpness and suppleness.

Moreover, formulations of natural dermal fillers may contain collagen and autologous fat. Natural collagen fillers are sourced from purified hyaluronic acid. Filler injections with body fat offer a holistic approach, reducing the risk of allergic reactions.

Benefits of Natural Dermal Fillers

Dermal filler injections with hyaluronic acid go beyond merely addressing cosmetic concerns, providing patients with various advantages that contribute to a more youthful appearance.

  • Stimulate natural collagen production: HA and collagen fillers stimulate the body’s own collagen production. This promotes long-term improvements in skin texture and elasticity.
  • Hydration and plumping effect: They help to restore volume, using the ability of hyaluronic acid to attract and retain water.
  • Natural-looking appearance: These dermal fillers mimic the body’s natural substances, ensuring seamless integration with existing tissues. They provide subtle enhancements and avoid an overly artificial or exaggerated look.
  • Minimized risk of allergic reaction: These kinds of injectables are safe and well-tolerated options, reducing the risks of side effects and allergies.
  • Gradual and adjustable results: The outcomes achieved with natural dermal fillers are often gradual, allowing for a more subtle and nuanced enhancement. Additionally, the adjustability allows for fine-tuning in follow-up sessions to meet specific patient preferences.
  • Versatility in treatment areas: This dermal filler treatment can treat moderate to severe facial wrinkles and folds, including nasolabial folds, marionette lines, and vertical lip lines.
  • Innovative technologies: Hyaluronic acid filler contains innovative formulations. The cross-linking technology allows the creation of a filler with varying degrees of thickness and flexibility. Varying molecular weights in the formulations allow a more targeted approach, designed to smooth deeper lines and wrinkles, or volumizing sunken areas.
  • Lidocaine integration: This local anesthetic in the composition enhances patient comfort during the injection process, reducing the need for additional anesthetic procedures to minimize discomfort.
  • Biocompatible formulations: Hyaluronic acid filler mimics the body’s natural substance. Thus, it can integrate seamlessly into the skin tissues and metabolize over time.

Duration of the Results

Natural dermal injectables are temporary solutions, as their effects fade over time. The longevity of results depends on the facial fillers used, the treatment area, metabolism, and lifestyle factors. The duration can range from 6 to 24 months.

Some hyaluronic acid fillers leverage advanced technologies to provide longer-lasting results. These formulations aim to slow down the natural breakdown of the filler, extending the duration of the cosmetic enhancement.

To sustain desired results, individuals may opt for maintenance sessions or touch-ups. These sessions involve additional injections to prolong the effects or refresh the appearance.

Brand Name Fillers

Juvederm, Restylane, and Revanesse are the most used dermal fillers, each with unique formulations and applications. They are composed mainly of hyaluronic acid, a naturally occurring substance in human bodies.

  • Juvederm injectable fillers smoothly integrate into soft connective tissues to add or restore volume and enhance contours. This brand is one of the most used filler treatments. It is known for its ability to provide natural-looking results and smooth lines.
  • Restylane offers a versatile lineup of facial fillers that provide skin rejuvenation, fill thin lips, and reduce vertical lip lines. Its fillers are gel-like substances. When Restylane is injected, it provides immediate visible improvement and a more natural appearance. It is a preferred choice for individuals seeking a more permanent solution to facial asymmetry and severe lines.
  • Revanesse is designed to restore lost volume, addressing areas with age-related volume loss and sagging skin. One of the distinguishing features of Revanesse is its lower rate of swelling compared to some other facial fillers.

All these fillers are associated with a fast recovery time. Patients can often resume their regular activities shortly after the procedure.

Synthetic Dermal Fillers

In contrast to natural counterparts, synthetic dermal injectables are composed of lab-made substances designed to provide long-lasting results.

Composition and Functionality

Synthetic dermal fillers are crafted using laboratory-manufactured substances — synthetic materials. They may include calcium particles, poly-lactic acids, and polymers. Their composition helps to address and smooth deep wrinkles and folds effectively.

Benefits of Synthetic Dermal Fillers

  • Calcium Hydroxylapatite (CaHa) fillers provide strong structural support to targeted areas. This is particularly beneficial for addressing facial volume loss and reshaping contours. One of the key benefits is their ability to stimulate the natural collagen production. This collagen-building effect enhances skin elasticity, texture, and longevity of results, making it an effective anti-aging solution. Calcium Hydroxylapatite filler is suitable for treating nasolabial folds, smile lines, and other facial contours.
  • Polylactic acid fillers are typically referred to as collagen stimulators. They induce the production of collagen in the skin. They are effective in addressing facial volume loss in hollow areas.

These injectables are biocompatible and compatible with human bones. This ensures natural breakdown over time without harm to the body tissues.

  • Polymethyl Methacrylate (PMMA) fillers act as a framework or scaffold, providing structural support. Also, they stimulate the synthesis of collagen over time. These actions enhance volume and fill wrinkles. PMMA injectables are often used to address severe fine lines and wrinkles, or areas with significant volume loss. The full effects may take several weeks to become apparent.

Unlike other facial fillers that are eventually absorbed by the body, the non-biodegradable nature of PMMA beads contributes to a more enduring correction.

Duration of the Results

Synthetic injectable dermal fillers are known for their long-lasting effects compared to other treatment options. These fillers offer durable volumization and structural support, resulting in extended benefits compared to other solutions. In general, the longevity lasts from 12 to 24 months. Additionally, advancements in filler formulations and injection techniques may lead to longer-lasting results.

Brand Name Fillers

  • Radiesse is a CaHa filler. It provides structural support and stimulates the production of collagen. Radiesse is effective in treating nasolabial folds and marionette lines.
  • Sculptra is made of Poly-lactic acid (PLLA). It stimulates the production of collagen over time, leading to gradual and long-lasting volume improvements. Sculptra is used for building up checks and addressing sunken areas of the face.
  • Bellafill consists of Polymethyl Methacrylate (PMMA) microspheres and bovine collagen (extracted from bones and connective tissues of the cow). Its components are in the smooth gel. They provide structural support and volume. The results are immediate and long-term as well.

These dermal filler products cater to different aesthetic goals and treatment preferences. The choice between them depends on individual needs. Some injectables provide temporary results, while others, like synthetic components, offer longer-lasting effects. Patients should consult with a board-certified cosmetic surgeon or plastic surgeons.

Considerations to Determine Suitable Treatment

When considering dermal filler treatment, there are important considerations to determine the most suitable option.

Personal Goals and Treatment Areas

Individual aesthetic objectives: Patients should understand their goals and desired outcomes of the treatment. Whether it’s reducing fine lines, adding volume to lips, or enhancing contours, defining goals guides the choice of injectable fillers.

Treatment areas: Different dermal injectables are suitable for specific areas of the face. For example, some solutions are designed for vertical lip lines, while others are better suited for deep wrinkles or sunken areas. Discuss with the patient and assess a targeted area to ensure the chosen filler aligns with area features.

Side Effects

Common side effects include redness, swelling, bruising, or tenderness at the injection site. These effects subside within a few days. Consider potential allergic reactions to filler ingredients. For instance, individuals with known allergies to certain substances, such as lidocaine or components of bovine collagen, should inform healthcare providers to avoid adverse reactions and minimize discomfort.

Note:Curious about the differences between Restylane and Botox? Explore our article ‘Restylane vs. Botox: Comparing Two Aesthetic Medicine Giants‘ for valuable insights into these popular treatments and how they can address your aesthetic concerns.

Conclusion

Choosing between natural and synthetic injectables is pivotal for clinics and healthcare providers to provide the desired treatment and outcome. Natural fillers, mostly hyaluronic acid fillers, offer versatility, subtle enhancement, immediate volume, and hydration of the skin tissues, resulting in smooth complexion and increased collagen development. On the other hand, synthetic injectables can support the structure of the face and have longer-lasting results. The selection of a suitable facial filler should align with patients’ preferences and goals.

Stay tuned for other explorations to be a well-informed professional. Thank you for reading!

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